Overview
- The August 2025 analysis found a 135% higher risk of cardiovascular death for people eating in less than eight hours daily versus a 12–14-hour window.
- The findings are observational and based on self-reported eating duration, yet the signal held across demographic and lifestyle subgroups and 14 sensitivity checks.
- The study did not find a consistent link with all-cause death or cancer mortality.
- An accompanying editorial by endocrinologist Anoop Misra advises individualized, supervised, short-term use and highlights risks for people with diabetes, older adults and those with chronic illness.
- Randomized trials show intermittent fasting can aid weight and metabolic markers, and an earlier retrospective analysis presented in 2024 linked a 16-hour fast to a 91% higher risk of heart-related death.