Overview

• A 12-week randomized trial involving 37 participants found a 3.7 mm Hg rise in systolic blood pressure after quitting snus, stabilizing at this level for two months.
• Participants also gained an average of 1.8 kilograms in weight, though the increase alone could not explain the blood pressure rise.
• Researchers speculate that disrupted autonomic regulation or other compensatory mechanisms may underlie the unexpected hypertensive response.
• The study highlights the need for routine cardiovascular monitoring and potential medication adjustments for individuals stopping snus, particularly those with pre-existing conditions.
• Future research is planned to explore the biological mechanisms behind these effects and to assess the impact of relapse on cardiovascular health.