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Study Finds Oral Immunotherapy Effective for Adults with Peanut Allergies

Phase two trial shows 67% of participants can tolerate five peanuts, offering hope to adults previously lacking treatment options.

Richard Lassiter's allergy is so severe that he has been admitted to hospital on multiple occasions after accidentally eating peanuts (Photo: Handout/PA Wire)
A breakthrough study shows that 'desensitisation' treatment may work on adults, a process that has already been shown to work on children (Photo: Jose Luis Pelaez Inc./Getty Images)
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Overview

  • A phase two study published in Allergy demonstrated that 67% of adult participants could consume the equivalent of five peanuts without severe reactions after oral immunotherapy.
  • The treatment involves gradually increasing exposure to small amounts of peanut protein to build tolerance under strict medical supervision.
  • This research addresses a long-standing gap in allergy treatments for adults, as prior desensitisation studies focused primarily on children.
  • Participants, including Richard Lassiter, described the therapy as life-changing, with Lassiter now consuming peanuts daily without fear of severe reactions.
  • Researchers emphasize the need for larger-scale studies to confirm findings and caution against attempting the therapy outside clinical settings.