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Study Finds One in Six Cancer Medications in Sub-Saharan Africa Defective

The findings highlight gaps in regulatory testing capacity, prompting the development of the low-cost chemoPAD screening tool.

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Overview

  • Analysis of 251 drug samples from Cameroon, Ethiopia, Kenya and Malawi revealed API levels skewing between 28% and 120% of labeled doses.
  • Only one in ten defective medications were caught by visual inspection, the prevailing screening method in the region.
  • Contributing factors include high demand, weaknesses in manufacturing and storage practices, and the absence of adequate regulatory capacity.
  • Sub-Saharan Africa currently has no laboratories equipped to perform chemical analyses of cancer drugs to global regulatory standards.
  • To address this gap, researchers are developing the chemoPAD, a low-cost paper-based device for point-of-care drug quality screening.