Overview

• Participants in the 4:3 intermittent fasting group lost 7.6% of their body weight over 12 months, compared to 5% in the daily calorie restriction group.
• The fasting group also showed better cardiometabolic outcomes, including improvements in blood pressure, cholesterol levels, and fasting glucose.
• Adherence to the intermittent fasting regimen may be higher due to reduced cognitive burden, as calorie counting is only required three days per week.
• The study included 165 overweight or obese adults aged 18–60, with participants receiving gym memberships, exercise guidance, and behavioral support.
• Researchers caution that findings may not be broadly applicable due to the single-site study design and predominance of women among participants (73.9%).