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Study Confirms Music Activates Brain’s Opioid System, Linking It to Pleasure and Pain Relief

Finnish researchers provide first neuroimaging evidence that favorite music triggers opioid release in key brain regions, revealing therapeutic potential for pain management.

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Overview

  • New research from the University of Turku shows that listening to favorite music directly activates the brain’s opioid system, similar to primary rewards like food and sex.
  • The study used neuroimaging on 30 women to identify increased opioid release in brain regions tied to emotion and reward, including the orbitofrontal cortex, amygdala, and nucleus accumbens.
  • Findings reveal that individual differences in opioid receptor density correlate with the intensity of pleasure experienced while listening to music.
  • The study, published in the European Journal of Nuclear Medicine and Molecular Imaging, highlights music's potential to alleviate chronic and postoperative pain by reducing reliance on opioid medications.
  • Researchers emphasize that culturally learned stimuli, such as music, can engage fundamental survival-related reward systems, bridging biological and aesthetic perspectives on pleasure.