Overview
- The Nature Medicine trial involved nearly 34,000 adults aged 40 and older with uncontrolled hypertension across 326 rural Chinese villages.
- Participants receiving intensive care saw their blood pressure drop significantly, with an average reduction to 127.6/72.6 mmHg, compared to 147.7/81.0 mmHg in the control group.
- Over four years, the intervention group experienced a 15% lower incidence of all-cause dementia and a 16% lower risk of mild cognitive impairment compared to standard care.
- The intervention included free or subsidized antihypertensive medications, lifestyle coaching, home monitoring, and tailored adherence support delivered by community healthcare providers.
- Researchers recommend scaling up this proven intervention globally to address the growing burden of dementia, which is projected to triple by 2050.