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Study at RSNA Finds Up to One in Four Breast Cancers Occur Before Age 50

A preliminary review from seven Western New York clinics reports a persistent quarter of diagnoses in women 18–49, prompting renewed focus on risk-based screening.

Overview

  • Researchers reviewed 2014–2024 records from seven outpatient centers and identified 1,799 breast cancers in 1,290 women aged 18–49.
  • Most tumors in this group were invasive (80.7%), with many biologically aggressive cases including triple-negative disease, particularly under age 40.
  • Younger women represented 21%–25% of those screened annually yet accounted for about one quarter of cancers each year.
  • Detection was split between 41% found on screening and 59% during diagnostic evaluation, underscoring gaps for patients younger than standard screening ages.
  • Authors urge individualized risk assessment and earlier surveillance for higher-risk patients, noting current U.S. guidance begins routine screening at 40–45 and that the meeting findings are regional and pending peer review.