Overview

• Jarrett Stidham replaced Bo Nix in the second quarter and completed 14 of 15 passes for 136 yards and two touchdowns to fuel Denver’s comeback.
• Bo Nix went 6 for 11 for 31 yards and was charged with a safety on an intentional grounding penalty before the Broncos turned to their backup quarterback.
• Denver played most of its starters for multiple series while the 49ers limited first-team reps and leaned heavily on reserves in the preseason opener at Levi’s Stadium.
• Joint practices in Santa Clara saw Broncos defenders repeatedly collapse the pocket, raising fresh doubts about San Francisco’s offensive line ahead of the regular season.
• San Francisco listed RB Ameer Abdullah, S Marques Sigle and LB Tatum Bethune as questionable after exiting the game with injuries, and Kyle Shanahan said rookie Mykel Williams should avoid a long-term setback from his hyperextended knee.