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Steelers Rookie Derrick Harmon Diagnosed With MCL Sprain, Expected to Miss 4–6 Weeks

The timeline raises roster decisions for Pittsburgh as Week 1 approaches.

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Derrick Harmon #99 of the Pittsburgh Steelers is carted off during the first half of the NFL Preseason 2025 game against the Carolina Panthers at Bank of America Stadium on August 21, 2025 in Charlotte, North Carolina.
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Overview

  • Harmon injured his knee in the preseason finale at Carolina and was carted off before being ruled out for the game.
  • Mike Tomlin initially called it a knee sprain, and subsequent reports identified an MCL sprain following evaluations.
  • NFL Network and local reporting place his recovery at roughly four to six weeks, putting his early-season availability in doubt.
  • The absence makes him a candidate for short-term injured reserve under the NFL’s four-game minimum, though no move has been announced.
  • The first-round pick was tracking to start on the defensive line, with short-term depth likely leaning on veterans such as Cameron Heyward, Keeanu Benton and Isaiahh Loudermilk.