Overview

• A South Korean study of over 570,000 adults found that individuals with LDL cholesterol levels below 1.8 mmol/L had a 26% lower risk of dementia and a 28% lower risk of Alzheimer's disease compared to those with higher levels.
• Statins provided additional protection, reducing dementia risk by 13% and Alzheimer's risk by 12% among people with low LDL cholesterol levels.
• The protective effect of low LDL cholesterol diminished at extremely low levels, with no benefit observed below 0.8 mmol/L.
• Researchers emphasized the need for targeted LDL management and further clinical trials to confirm causation and explore the mechanisms behind these effects.
• Experts suggest maintaining heart health through lifestyle changes and medical interventions as an effective strategy for reducing dementia risk.