Statins Linked to Reduced Dementia Risk, Study Finds
New research highlights the protective role of statins and low LDL cholesterol levels in lowering dementia risk, though extremely low levels may negate benefits.
- A South Korean study of over 570,000 adults found that individuals with LDL cholesterol levels below 1.8 mmol/L had a 26% lower risk of dementia and a 28% lower risk of Alzheimer's disease compared to those with higher levels.
- Statins provided additional protection, reducing dementia risk by 13% and Alzheimer's risk by 12% among people with low LDL cholesterol levels.
- The protective effect of low LDL cholesterol diminished at extremely low levels, with no benefit observed below 0.8 mmol/L.
- Researchers emphasized the need for targeted LDL management and further clinical trials to confirm causation and explore the mechanisms behind these effects.
- Experts suggest maintaining heart health through lifestyle changes and medical interventions as an effective strategy for reducing dementia risk.