Overview
- Ox Nche returns at loosehead in the only change to the starting lineup, with Bongi Mbonambi, Grant Williams and Jesse Kriel added to a 5–3 split bench.
- Franco Mostert remains in South Africa following a family bereavement, and Lood de Jager has linked up in London fully fit as experienced cover.
- South Africa lead the standings by one point, so a win over Argentina would secure back-to-back Rugby Championship titles, with a bonus-point victory guaranteeing the crown.
- Rassie Erasmus kept faith with the Durban-winning core after a record 43-10 defeat of New Zealand and a 67-30 win over Argentina, when Sacha Feinberg-Mngomezulu scored a Springbok record 37 points.
- The match will be played at Twickenham after Argentina opted to stage it in England for commercial reasons.