Overview

• Fresh FEC/ESFEC data show 57.3% of Spaniards carry two or more cardiovascular risk factors and 22.8% have hypercholesterolemia.
• Cardiovascular disease accounts for more than a quarter of deaths in Spain, with 13 people dying every hour and over 120,000 heart attacks or angina cases annually.
• The 2025 ESC guidance lowers LDL goals by risk tier—from under 115 mg/dL for low risk to under 55 mg/dL for very high risk—broadening indications for pharmacologic therapy after lifestyle measures.
• Doctors cite low awareness, therapeutic inertia and poor adherence as key barriers, even as they note that up to 80% of premature cardiovascular deaths could be prevented with healthier habits.
• High‑risk groups flagged include women around menopause, whose LDL can rise about 10% at that transition, and people with familial hypercholesterolemia—around 1,600 births a year in Spain—as well as some young patients.