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SKUAST Researchers Produce India’s First Gene-Edited Sheep with 30% More Muscle

Silencing the myostatin gene without foreign DNA sets the stage for regulatory approval under India’s new biotech policy.

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Overview

  • After a four-year program, scientists at Sher-e-Kashmir University used CRISPR-Cas9 to disrupt the myostatin gene in a lamb, enhancing its muscle mass by nearly 30%.
  • The edited sheep contains no foreign DNA, distinguishing it from transgenic organisms and meeting international biosafety standards.
  • Vice Chancellor Nazir Ahmad Ganai briefed Lieutenant Governor Manoj Sinha on the breakthrough, advancing preparations for policy approval and farmer-level use.
  • Sponsored by the Indian Council of Agricultural Research, the achievement follows the country’s first gene-edited rice variety and underscores India’s push towards a sustainable bioeconomy.
  • The technology offers potential for developing disease-resistant herds and increasing twinning rates in livestock, positioning SKUAST-Kashmir as a leader in reproductive biotechnology.