Overview
- Researchers analyzed 481 people during a first episode of psychosis and followed outcomes after four weeks of antipsychotic treatment.
- Dermatological signs were present in 14.5% of participants overall, including 24% of females and 9.8% of males.
- About 25% of patients with initial skin complaints reported suicidal thoughts or attempts at follow-up, compared with roughly 7% without skin issues.
- The team proposes shared developmental origins and inflammatory pathways as possible explanations, though mechanisms remain unconfirmed.
- Independent experts welcomed the signal but emphasized the need for replication in other cohorts, longer follow-up, and mechanistic studies before adopting this as a risk marker.