Overview
- Mac Jones completed 33 of 49 passes for 342 yards and two touchdowns with no interceptions, returning after a knee scare and guiding an injury-thinned offense.
- Rookie Alfred Collins forced and recovered a goal-line fumble late in regulation, and the defense stuffed a fourth-and-1 at the San Francisco 11 in overtime as Sean McVay later expressed regret over the call.
- Eddy Piñeiro hit all four field goals, including a 59-yarder in the fourth quarter and the 41-yard game-winner in overtime.
- Brock Purdy was inactive with a turf toe injury and remains week-to-week as Adrian Martinez was elevated to the active roster and several key pass catchers, including George Kittle, Brandon Aiyuk, Ricky Pearsall and Jauan Jennings, were out.
- San Francisco won outright as an 8.5-point underdog, its first such upset since 2011 per ESPN Insights, to improve to 4-1.