Overview
- ARC Innovation at Sheba and Mount Sinai will supply large clinical and genomic datasets and domain expertise, while NVIDIA provides GPU infrastructure, software and scientific support.
- The initiative seeks to decode the largely uncharted noncoding regions of the genome to uncover regulatory mechanisms tied to disease risk and treatment response.
- The work is anchored in Mount Sinai’s Million Health Discoveries Program and Sheba’s ARC Innovation hub, co-led by ARC’s AI Center and Mount Sinai’s Charles Bronfman Institute and Windreich Department.
- Joint teams have started platform development with significant multi‑year investments committed, with the current phase focused on data aggregation, governance and compute provisioning before model training.
- Leaders emphasize the scale of the task, describing a model that treats DNA like a language and requires immense GPU power and multidisciplinary collaboration, with the goal of accelerating precision medicine research.