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Severe Strokes Carry Fivefold Dementia Risk, Large U.S. Study Finds

The results point to routine cognitive checks for stroke survivors with tighter control of blood pressure, blood sugar, and cholesterol.

Overview

  • Peer-reviewed findings in JAMA Network Open report that the most severe strokes are linked to roughly five times higher odds of developing dementia.
  • The study tracked more than 42,000 U.S. adults, including about 1,500 stroke survivors, for as long as three decades.
  • Dementia risk rose stepwise by stroke severity, about doubling after minor strokes and tripling after moderate strokes compared with no stroke.
  • Stroke survivors declined faster in overall thinking, memory, and executive function, equal to starting 1.8 to 2.6 years older depending on stroke severity.
  • The authors recommend routine cognitive follow-up for all stroke survivors with strict management of cardiovascular risks to reduce further decline.