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Severe Asthma Study Maps Three Common Comorbidity Profiles Across Europe

Researchers say the patterns could steer more targeted care for patients with poor asthma control.

Overview

  • The peer-reviewed analysis, published Wednesday in The Lancet Regional Health Europe, pooled registry data on 2,700 people with severe asthma from 11 countries.
  • Nearly all participants had at least one other major long-term condition, and most were living with three or more.
  • Researchers identified three repeatable profiles: high steroid use linked to osteoporosis and weight gain, severe allergies such as eczema and allergic rhinitis, and chronic sinusitis with nasal polyps.
  • The clusters were tied to how well symptoms were controlled, how often attacks occurred, and which treatments patients required.
  • The work, done within the SHARP and European Respiratory Society collaboration, points to care pathways that cut oral steroid use and improve day-to-day quality of life.