Overview
- The quarterfinals will feature Giana Erminio vs. Ternana, Crotone vs. Vicenza, Vis Pesaro vs. Pescara, and Atalanta U23 vs. Audace Cerignola.
- The draw confirmed seeded teams—Vicenza, Ternana, Audace Cerignola, and Pescara—will host the second legs and progress in the event of tied aggregates.
- First-leg matches are scheduled for May 18, with return legs on May 21, as teams compete for advancement to the Final Four stage.
- Pescara, despite losing 2-1 to Catania in the first round, advanced as the best-ranked winner and joins the three second-place regular-season teams as a seeded side.
- All third-place regular-season teams were eliminated in the first national playoff round, marking a significant shift in the competition's dynamics.