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Self-Guided Hypnosis Halves Menopausal Hot Flashes, JAMA Trial Finds

The home program offers a nonhormonal option for women who cannot use hormone therapy.

Overview

  • The JAMA Network Open randomized trial enrolled 250 postmenopausal women to six weeks of self-hypnosis audios or a white-noise sham.
  • Hot-flash scores fell 53.4% at six weeks with hypnosis versus 40.9% with the sham, based on participants’ daily diaries.
  • At 12 weeks, the hypnosis group showed a 60.9% reduction with greater gains in sleep, mood, concentration and overall quality of life.
  • Women with a history of breast cancer saw larger early effects, with about a 64% reduction after six weeks.
  • Researchers highlight the active control design, home-based delivery and low cost, while noting unclear mechanisms and the need for longer-term data.