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Seattle Biotech Hub Developing 'DNA Typewriter' to Record Cellular Changes

The $75 million project, a collaboration between the University of Washington, the Chan-Zuckerberg Initiative, and the Allen Institute, aims to transform cells into tiny recording devices for a deeper understanding of cellular processes.

  • Seattle Hub for Synthetic Biology, a collaboration between the University of Washington, the Chan-Zuckerberg Initiative, and the Allen Institute, is developing technology to transform cells into tiny recording devices.
  • The project, funded by $75 million from tech billionaires, aims to use genetically modified cells to capture a DNA-based record showing how they change over time.
  • The technology, likened to a 'DNA typewriter', could lead to a deeper understanding of cellular processes, including disease progression and healthy cell growth.
  • Two techniques, DNA Typewriter and Engram, are being developed to record and assign meanings to biological signals over time.
  • Findings from the research will be shared widely within the scientific community, with potential applications in studying cell multiplication, tissue engineering, and disease treatment.
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