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Season 2 of 'The Secret Lives of Mormon Wives' Opens with Ketamine Therapy Focus

Jen and Zac Affleck's ketamine session highlights mental health treatment innovation within Mormon culture as the show premieres on Hulu and Disney+.

Taylor Frankie Paul (left) and Jen Affleck (right) in a scene from "The Secret Lives of Mormon Wives."
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Overview

  • The second season of 'The Secret Lives of Mormon Wives' premiered on May 15, 2025, featuring Jen and Zac Affleck undergoing ketamine therapy in the first episode.
  • Ketamine therapy, used for depression, anxiety, and PTSD, involves supervised administration of the drug to disrupt cycles of negative thought patterns.
  • Jen Affleck described ketamine as existing in a doctrinal 'gray area' for the LDS Church, neither promoted nor explicitly prohibited.
  • The therapy session underscores the couple's commitment to their marriage, with Jen calling Zac's participation a testament to his dedication.
  • While ketamine is widely used off-label for mental health in the U.S., it remains unlicensed for such purposes in the U.K., highlighting regulatory differences.