Overview
- Kickoff is 8:15 p.m. ET at State Farm Stadium in Glendale, with national streaming on Amazon Prime Video.
- Both teams enter 2-1 in the NFC West, and sportsbooks price Seattle around -1.5 with a total near 43.5.
- Arizona will play without running back James Conner for the rest of the year after foot surgery, shifting more work to Trey Benson and passing-game focal point Trey McBride.
- Seattle’s defense has been among the league’s stingiest and is reinforced by the returns of Julian Love and Devon Witherspoon after both sat out Week 3.
- The Seahawks have won seven straight against the Cardinals, including four in a row in Glendale, and arrive after a 44-13 rout of the Saints.