Overview
- Seattle clinched the NFC West and top seed as the 49ers fell to 12-5, with San Francisco slotted as the No. 5 seed if the Rams lose or tie and the No. 6 seed if Los Angeles wins.
- San Francisco managed just 173 yards and nine first downs, with Brock Purdy going 19-of-27 for 127 yards with one interception and three sacks.
- Left tackle Trent Williams (hamstring) and wide receiver Ricky Pearsall (knee/ankle) were inactive, and Austen Pleasants made his first NFL start at left tackle.
- Kyle Shanahan said Purdy sustained a shoulder stinger on the final series but could have returned, while linebackers Dee Winters (ankle) and Tatum Bethune (groin) exited and did not return; Luke Gifford (quad) came back.
- A tipped pass intended for Christian McCaffrey was bobbled and intercepted by Drake Thomas at the 6-yard line, halting the 49ers’ best scoring chance in the fourth quarter.