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Seahawks Host 49ers in NFC Divisional Rematch With Odds and Defense Favoring No. 1 Seed

Seattle's top-ranked defense at the NFC's No. 1 seed presents a short‑week road test for an injury-hit 49ers squad.

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Niners quarterback Brock Purdy runs while shadowed by Seattle Seahawks linebacker Cody Barton during the first half in Seattle on Dec. 15, 2022. 
Seahawks defensive end DeMarcus Lawrence chases 49ers quarterback Brock Purdy during the season opener on Sept. 7 in Seattle.
Niners then-rookie quarterback Brock Purdy, who received a painkilling injection before the game, celebrates after defeating the Seahawks 21-13 in Seattle on Dec. 15, 2022.

Overview

  • Kickoff is Saturday, Jan. 17 at Lumen Field (8:15 p.m. ET on FOX) in a third meeting after the teams split the regular season series.
  • Oddsmakers list Seattle around a touchdown favorite with a mid-40s total as analysts anticipate a lower-scoring game.
  • San Francisco lost TE George Kittle to a torn Achilles in the Wild Card win and travels cross‑country on a short week after beating the Eagles.
  • Brock Purdy is 4-0 as a starter in Seattle and with a win would reach six career postseason victories through four seasons, tying Tom Brady and Patrick Mahomes for second-most in that span.
  • Seahawks QB Sam Darnold was added to the injury report with an oblique issue and is listed questionable, though he said he expects to play after Seattle’s defense held the 49ers to 13-3 in Week 18.