Overview

• Kickoff is 8:15 p.m. ET at State Farm Stadium in Glendale, with national streaming on Amazon Prime Video and local over-the-air broadcasts in the Seattle and Phoenix markets.
• Both teams enter 2-1 with their lone losses to the 49ers, setting up an early divisional tiebreaker opportunity in the NFC West.
• Cardinals running back James Conner is out for the season following foot surgery, elevating roles for Trey Benson and receiving targets like Trey McBride and Marvin Harrison Jr.
• Seattle lists corner Devon Witherspoon and safety Julian Love as available, and running back Zach Charbonnet is expected to play after a full Wednesday practice.
• Seattle has a seven-game winning streak over Arizona, and by Thursday afternoon major sportsbooks had the Seahawks at -1.5 with totals around 43.5.