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Scientists Unveil Molecular Structures of Alzheimer's Proteins

Groundbreaking imaging techniques reveal detailed architecture of β-amyloid plaques and tau filaments in human brain tissue.

  • Researchers used cryo-electron tomography and fluorescence microscopy for unprecedented insights.
  • Study focused on β-amyloid plaques and tau filaments, key in Alzheimer's pathology.
  • Findings show how these proteins disrupt cellular communication, leading to symptoms.
  • Research could pave the way for new therapeutic targets and diagnostic tools.
  • Collaboration involved University of Leeds, Amsterdam UMC, Zeiss Microscopy, and University of Cambridge.
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