Scientists Map DNA Repair Processes in Individual Human Cells

New research reveals how repair proteins form 'hubs' to efficiently fix DNA damage, offering potential for improved cancer treatments.

Researchers at the Hubrecht Institute have mapped DNA repair protein activity in individual human cells for the first time.
The study highlights how repair proteins collaborate in 'hubs,' centralizing multiple DNA damage sites for coordinated repair.
These findings provide insights into why some DNA regions are harder to repair and how repair mechanisms vary between cells.
The research, published in *Nature Communications*, could inform the development of more effective and less harmful treatments for cancer and genetic disorders.
Understanding DNA repair processes at a granular level may enable targeted therapies that exploit specific repair mechanisms.