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Scientists Identify 'Meal Memory' Neurons That Regulate Hunger and Satiety

Eating pauses drive meal engram formation shaping hunger, with implications for obesity therapy.

Overview

  • Meal memory neurons in the rat ventral hippocampus encode when and where food is consumed through specialized engrams.
  • These neurons communicate with the lateral hypothalamus to modulate hunger signals and influence eating behavior.
  • Blocking the hippocampus-hypothalamus pathway causes lab rats to overeat and lose recall of recent meals.
  • Distracted eating disrupts meal engram formation, leading to mindless snacking and increased food intake.
  • Researchers suggest that reinforcing meal memory through mindful eating practices could inform new obesity treatments.