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Scientists Identify 'Meal Engram' Neurons That Shape Eating Behavior

Researchers say boosting these meal memories may be as crucial for weight control as diet or exercise.

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Overview

  • Researchers at USC used advanced neuroscience techniques to track ventral hippocampus activity and found specialized neuron groups form 'meal engrams' during brief pauses between bites.
  • Disrupting these meal engram neurons in rats impaired their memory of food locations without affecting other spatial memories.
  • Blocking the hippocampus-hypothalamus pathway led rats to overeat and forget where they had consumed meals.
  • Distracted eating, such as snacking while watching television, weakened meal memory formation and may drive overeating.
  • The findings suggest that strengthening meal recall could become a target for obesity treatments alongside diet and exercise.