Scientists Engineer Parasite to Deliver Drugs Directly to the Brain

Innovative use of Toxoplasma gondii offers new potential for treating neurological disorders

Researchers have genetically modified Toxoplasma gondii to transport therapeutic proteins into brain cells.
This method aims to overcome the blood-brain barrier, which limits drug delivery to the brain.
The engineered parasite secretes proteins that can regulate gene activity within neurons.
Initial studies show promise for treating conditions like Rett syndrome and possibly Alzheimer's and Parkinson's.
Despite its potential, the approach requires significant safety modifications before clinical application.