Overview

• Researchers have genetically modified Toxoplasma gondii to transport therapeutic proteins into brain cells.
• This method aims to overcome the blood-brain barrier, which limits drug delivery to the brain.
• The engineered parasite secretes proteins that can regulate gene activity within neurons.
• Initial studies show promise for treating conditions like Rett syndrome and possibly Alzheimer's and Parkinson's.
• Despite its potential, the approach requires significant safety modifications before clinical application.