Scientists Discover Key Molecular Defect in Lupus

New research identifies a defect in immune cell regulation, offering potential targeted treatments for the autoimmune disease.

Researchers found an imbalance in T cells, leading to excessive harmful cells and insufficient protective ones.
The study highlights the role of the aryl hydrocarbon receptor (AHR) in regulating immune responses.
Activating AHR could reprogram harmful cells to become protective, suggesting a new therapeutic strategy.
Current treatments broadly suppress the immune system, while this approach targets specific disease-causing cells.
Further research is needed to confirm the effectiveness and safety of AHR-targeting therapies in humans.