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Scientists Develop Urine Test for Early Lung Cancer Detection

The test, which identifies proteins linked to cancer development, has shown success in mice and is moving toward human trials.

  • Researchers at the University of Cambridge have created a urine test that detects proteins from senescent 'zombie' cells, which are linked to the early stages of lung cancer.
  • The test uses an injectable sensor that interacts with these proteins and releases a detectable compound into urine, signaling potential cancer development.
  • This innovation aims to address the challenge of late-stage lung cancer diagnoses, which currently account for nearly half of all cases in the UK.
  • The test has been successfully trialed in mice, and scientists are preparing for further validation and eventual human clinical trials.
  • The project, funded by Cancer Research UK, could provide a cost-effective alternative to expensive scans and may be expanded to detect other cancers such as breast, melanoma, and pancreatic.
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