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Scientists Develop Pill Mimicking Exercise Benefits

A groundbreaking pill that simulates the health benefits of physical exercise could revolutionize treatment for muscle atrophy, heart failure, and neurodegenerative diseases.

pill and exercise
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It could also potentially counter the effects of other drugs, such as new weight-loss medications that cause the loss of both fat and muscle, according to Elgendy. Credit: Neuroscience News

Overview

  • Researchers have created a compound, SLU-PP-332, and its derivatives that activate key proteins to mimic the effects of exercise in muscle metabolism and growth.
  • The exercise-mimicking pill could provide an alternative for those unable to engage in regular physical activity due to age, disease, or dislike of exercise.
  • The compounds have shown promise in rodent models, improving endurance and muscle fiber strength, and are expected to undergo further preclinical testing.
  • This innovation has potential applications in treating muscle weakness, obesity, heart failure, and possibly neurodegenerative diseases, offering new hope for patients.
  • Future studies will focus on developing compounds that can cross into the brain, targeting neurodegenerative disorders more effectively.