Overview

• FDA officials say they have initiated changes to acetaminophen labeling to note studies suggesting associations with autism and ADHD, while acknowledging causation is unproven.
• President Donald Trump publicly urged pregnant women to avoid Tylenol and the administration outlined plans for label changes, physician notices and a public awareness campaign.
• A Nature editorial criticized the administration’s framing as cherry‑picking and highlighted large sibling‑comparison studies in Sweden and Japan that found no conclusive association when controlling for familial factors.
• International regulators including the WHO and EMA, along with U.S. professional bodies such as ACOG and the American Academy of Pediatrics, state guidance is unchanged and continue to recommend judicious acetaminophen use in pregnancy.
• New reactions include autism experts at a House Democratic Policy Committee session and clinicians in media interviews stressing fever treatment’s benefits and warning that discouraging acetaminophen could increase harm, as polling in the UK shows most still consider paracetamol safe.