Scientists Achieve Breakthrough in Reviving Frozen Human Brain Tissue

New chemical solution enables brain organoids to maintain structure and function after thawing, paving the way for advanced neurological research.

Researchers at Fudan University developed a chemical mixture called MEDY to preserve brain tissue during freezing.
The mixture includes methylcellulose, ethylene glycol, DMSO, and Y27632, preventing cell death during the thawing process.
Brain organoids frozen in MEDY for up to 18 months showed similar growth and function to non-frozen counterparts.
The technique was successfully tested on brain tissue from a 9-month-old epilepsy patient, maintaining its pre-freezing structure.
This advancement could revolutionize the study of neurological conditions and potentially lead to whole-brain cryopreservation.