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Santa Fe Hospital Performs Latin America’s First Adult Heart Donation Using Controlled Asystole

The public center applied Argentina’s 2023 asystole protocol with a highly trained team to broaden the donor pool.

Overview

  • Hospital José María Cullen retrieved a heart, liver and kidneys after controlled cardiac arrest in an adult, enabling three transplants.
  • Two recipients were treated in Santa Fe and one in Córdoba, according to provincial health officials and CUDAIO.
  • With this operation, the hospital reached 47 donation procedures in 2025, surpassing its previous annual record set in 2015.
  • Controlled asystole requires precise timing, specialized ICU capacity and extracorporeal support, following a protocol aligned with Law 27.447.
  • Santa Fe’s health ministry cited over 2.2 billion pesos spent on post‑transplant medicines due to reduced national coverage, with more than 7,000 people awaiting transplants nationwide and over 500 in the province.