Overview

• Rosie O'Donnell shared a photo on Instagram on May 23, 2025, showcasing her significant weight loss and expressing disbelief at her transformation.
• The 63-year-old comedian attributes her weight loss to the diabetes medication Mounjaro, which she has been using since November 2022, and healthier lifestyle habits.
• O'Donnell has reduced sugar intake, switched to drinking only water, and now cooks meals for herself and her 12-year-old child after moving to Ireland.
• She has been open about her long-standing struggles with weight, previously undergoing gastric sleeve surgery in 2013 after a heart attack in 2012.
• Mounjaro, prescribed for type 2 diabetes, has gained attention for its weight-loss effects and has been used by other celebrities such as Elon Musk and Meghan Trainor.