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RKI: Infant RSV Cases and Hospitalizations More Than Halved After Antibody Rollout

Researchers attribute the sharp decline to the new infant antibody prophylaxis rather than seasonal swings.

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Overview

  • National surveillance recorded about 1,045 RSV cases per 100,000 infants in 2024/25, down from roughly 2,290 in 2023/24.
  • Hospital admissions fell from around 6,480 in 2023/24 to just under 2,900 in 2024/25, and ICU cases declined from 121 to 55.
  • STIKO has recommended the antibody protection for all newborns and infants since June 2024 ahead of their first RSV season.
  • The intervention is a passive immunization in which preformed antibodies are administered rather than eliciting an immune response.
  • RKI reported hospital admission data for about two-thirds of infant cases, and the analysis was published in Deutsches Ärzteblatt.