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Right Uncinate Fasciculus Integrity Predicts Social Dominance in Squirrel Monkeys

Tractographic analysis shows a clear link from right uncinate fasciculus integrity to hierarchy behaviors in squirrel monkeys under rigorous control conditions.

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These findings support human studies linking this brain region to social aggression, suggesting this may be an evolutionarily conserved substrate for social dominance across species. Credit: Neuroscience News

Overview

  • Researchers used diffusion MRI tractography to examine limbic white matter pathways in 15 squirrel monkeys.
  • Social dominance measures included normalized David’s scores along with observed aggression and submissive behaviors.
  • Integrity of the right uncinate fasciculus showed the strongest correlation with higher social rank.
  • Trends in the left uncinate fasciculus suggest potential bilateral involvement despite a clear right-hemispheric lateralization.
  • The fornix served as a control tract and analyses accounted for age, weight, handedness, brain size and hormone levels to isolate dominance-related effects.