Overview
- HHS has withdrawn roughly $500 million across 22 BARDA and NIH-backed mRNA vaccine development projects targeting late-stage flu, COVID and infectious disease trials.
- The department’s public statement frames the wind-down as refocusing away from emergency-phase work and restoring confidence in vaccine science.
- Independent reviewers, including STAT, say the 181-page bibliography cited by HHS is not a systematic analysis and does not support terminating mRNA research.
- Experts warn the cancellations remove funding for Phase 3 trials, manufacturing scale-up and stockpiling that only BARDA typically underwrites, risking U.S. pandemic preparedness.
- Researchers contend the cuts could chill innovation in mRNA applications beyond infectious diseases, from personalized cancer vaccines to gene-editing therapeutics.