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Revolutionary Microscope Captures Nanoscale Biological Processes in Real Time

Researchers unveil a groundbreaking technique to visualize live biological processes with unprecedented detail, revealing insights into arterial calcification.

  • Scientists at Radboud University Medical Center have developed a new microscope capable of imaging live biological processes at the nanoscale, allowing visualization of moving protein complexes.
  • The technique overcomes previous limitations by using a protective graphene layer and a non-reactive fluorescent dye to minimize damage from the electron beam.
  • This method enables the freezing and subsequent thawing of biological samples, allowing researchers to capture dynamic processes without delay.
  • Initial demonstrations of the technique have provided new insights into how calcium deposits form in arteries, which could lead to calcification.
  • The research team plans to further explore arterial calcification using this technology, with future projects including the development of a 'heart valve on a chip' model.
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