Overview
- Candida auris has now been reported in at least 61 countries across six continents, according to the new review.
- The fungus adheres strongly to human skin and surfaces, facilitating colonization and hospital transmission.
- Resistance is driven by traits including yeast‑to‑filament switching, efflux pumps that expel drugs, and hard‑to‑penetrate biofilms.
- Invasive fungal infections affect roughly 6.5 million people annually and can carry mortality rates above 50 percent even with treatment.
- Authors call for better diagnostics, surveillance and vaccine or immune‑based strategies, noting three antifungal drugs are in trials or late‑stage development.