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Resistance to Key Malaria Drug Detected in African Children

A study reveals partial resistance to artemisinin in Ugandan children with severe malaria, raising concerns over treatment efficacy.

  • Researchers found that 11% of Ugandan children with severe malaria showed partial resistance to artemisinin, a crucial drug.
  • The study involved 100 children hospitalized with severe malaria, revealing genetic mutations linked to drug resistance.
  • Partial resistance was identified for the first time in African children with severe malaria, a group highly vulnerable to the disease.
  • 10 children experienced a recurrence of malaria, suggesting possible resistance to the partner drug lumefantrine.
  • Experts warn that if resistance spreads, it could significantly impact malaria treatment guidelines and increase mortality rates.
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