Overview

• Two lead compounds integrated into bed-net prototypes achieve 100% Plasmodium parasite kill at very low concentrations and retain activity for at least one year.
• The compounds remain effective when applied to mosquitoes up to four days before infection, reducing their potential to become infectious.
• Unlike traditional insecticide-treated nets, this approach targets the parasite without killing mosquitoes, reducing resistance risks and extending net lifespan.
• Prototypes include polyester nets coated with antimalarial solutions and polyethylene nets embedded with drugs via hot-melt extrusion for sustained release.
• The cost-effective production methods and compatibility with existing net infrastructure position the technology for scalable deployment in malaria-endemic regions.