Overview

• Ex vivo tests demonstrated that pairing optimized scalp cooling at 18°C with a topical antioxidant lotion fully protects hair follicles from chemotherapy damage.
• Sheffield Hallam University researchers determined that cooling to 18°C is essential for follicle preservation, while 26°C proved insufficient.
• The antioxidant formulation, containing resveratrol and N-acetylcysteine, boosts the protective effect of cooling by countering oxidative stress.
• Paxman’s adapted scalp cooling system administers the combined therapy in half-hour pre-treatment, during chemotherapy, and up to 90 minutes post-treatment sessions.
• Following the July 9 publication of these lab results, the team is finalizing lotion formulations and coordinating clinical trials to assess real-world efficacy.