Overview
- Large cohort data from the Nurses’ Health Study link higher gratitude in nearly 49,000 older women to a 9% lower four‑year mortality risk.
- A UCLA review of roughly 70 studies finds gratitude is associated with lower depression and higher self‑esteem, though effects vary in size and duration.
- Lab work from UC San Diego shows expressing thanks before a stressful task produces healthier cardiovascular responses and improves teamwork, with other‑focused thank‑yous strengthening bonds most.
- Physiology and neuroscience reports describe activation of the parasympathetic relaxation response and changes in brain reward and empathy circuits during gratitude practice.
- Clinicians and researchers recommend accessible, consistent habits—journaling, letters, micro‑moments, prompts and pairing gratitude with daily routines—tailored to the individual rather than used as a stand‑alone treatment.