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Research Proposes Measles Vaccine at Four Months as Global Cases Surge

Waning maternal antibodies erode protection by four months, prompting New Zealand to recommend an early measles dose for traveling infants

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A graphic showing a hand holding a needle and vaccine bottle, imposed ontop of a vaccine schedule and a navy blue background
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Overview

  • A Murdoch Children’s Research Institute review shows maternal measles antibodies drop from 81% at birth to 30% by four months in low- and middle-income settings.
  • Administering a first measles dose between four and seven months of age elicits a strong immune response in infants.
  • Nearly 400,000 measles cases were reported in 2024 and over 16,000 in early 2025, with COVID-19 disruptions and rising hesitancy undermining routine immunization.
  • Experts warn that achieving the 95% two-dose coverage needed for herd immunity remains a major global challenge.
  • New Zealand now advises an additional measles shot at four months for infants traveling to regions with active transmission.