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Reports: CardinalsJames Conner To Undergo Ankle Surgery, Season Likely Over

Trey Benson moves into the lead role pending the team’s full medical update.

Overview

  • Conner suffered a severe right ankle injury in the third quarter at Levi's Stadium, was carted off, and was ruled out for the game.
  • NFL Network’s Ian Rapoport reports he will have surgery and is out indefinitely, while ESPN’s Adam Schefter and Josh Weinfuss report expectations he will miss the rest of 2025.
  • Head coach Jonathan Gannon confirmed the injury was to Conner’s ankle but said after the game the severity was still unknown.
  • The veteran finished with nine carries for 22 yards and three receptions for 15 yards in a 16-15 loss to the 49ers.
  • With Conner unavailable, the Cardinals plan to feature Trey Benson, with Emari Demercado and Bam Knight in support and practice-squad back Michael Carter a potential elevation.